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The development of research techniques for postmarketing surveillance using Clinical data warehouse


Purpose

The development of research techniques for postmarketing surveillance(PMS) using Clinical data warehouse
- research on adverse drug reaction in hospital information system
- Building Clinical Data warehouse for PMS of subject drug
- Development of knowledge rule for selecting adverse drug reaction
- Development of selecting techiques for case-control using Propensity score maching
- Development of performing techiques for analytical drug epidemiology
- Develpment of comparing techiques for adverse drug reaction about pre-post administration of subject drug

Contents

Reserch on data about Adverse drug reaction in hospital Information system
-research on hospital database related to adverse drug reaction
-understanding and re-defining data attributes for building data warehouse¡à Building Clinical Data warehouse for PMS of subject drug
-Performing 'Extract, Transform, Load'
-Development of techiques for data quality management
-Designing and implementation for and architecture of huge data warehouse
Development of knowledge rule for selecting adverse drug reaction
-Research on types of adverse drug reaction for each drug
-Modeling a knowledgebase and adverse drug reaction rules
Development of selecting techiques for case-control using Propensity score maching
-Case-control selection using Knowledgebase
-Performing the propensity score matching through Clinical data warehouse
Development of performing techiques for analytical drug epidemiology
-Basic descriptive statistics
-Development of comparison techiques for incidence of adverse drug reacion for case-control
Develpment of comparison techiques for adverse drug reaction about pre-post administration of subject drug

Expected Contribution

Applying to every clinical trial center after developing PMS techiques available to monitor adverse drug reaction which is founded in enviroment of real clinical trials for various patients with low cost
Utilization as national drug safety management system through expansion of various PMS system
Reducing the cost and period for PMS
Contribution for patient safety through continuous PMS of subject drugs


<System Overview>

 


PharmacoVigilance
 

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  *ECG-ViEW
   

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Department of Biomedical Informatics, Ajou University School of Medicine
442-753, Wonchun-dong, Suwon, Republic of Korea